The Complete Guide to AI Agent Frameworks in 2024
A comprehensive 3000+ word guide covering all major AI agent frameworks, their architectures, strengths, use cases, and how to choose the right one for your project
When building AI agents in Python, two frameworks dominate the conversation: LangChain and LlamaIndex. Both enable you to build sophisticated applications powered by large language models, but they evolved from different starting points and excel in different scenarios. This comparison breaks down their architectures, strengths, and ideal use cases to help you choose the right tool for your project.
LangChain launched in late 2022 as a framework for “chaining” together different components in LLM applications. Its original insight was that powerful applications require more than just prompting a model—they need structured workflows connecting prompts, models, tools, and memory.
Core philosophy: LangChain treats LLM applications as compositions of modular components. You build by connecting chains, agents, tools, and memory systems. The framework prioritizes flexibility and supports almost any architecture you can imagine.
LlamaIndex (originally GPT Index) emerged from the observation that connecting LLMs to external data was the most common and challenging task developers faced. It started as a data framework for LLMs, providing sophisticated indexing, retrieval, and data transformation capabilities.
Core philosophy: LlamaIndex treats data as the central challenge. It provides opinionated, optimized patterns for ingesting, structuring, and querying data with LLMs. The framework prioritizes getting data retrieval right.
LangChain organizes functionality into several packages:
A typical LangChain agent setup looks like this:
from langchain_openai import ChatOpenAI
from langchain.agents import create_tool_calling_agent, AgentExecutor
from langchain_core.prompts import ChatPromptTemplate
from langchain_community.tools import TavilySearchResults
# Initialize components
llm = ChatOpenAI(model="gpt-4o")
search_tool = TavilySearchResults(max_results=3)
# Define agent prompt
prompt = ChatPromptTemplate.from_messages([
("system", "You are a helpful research assistant."),
("human", "{input}"),
("placeholder", "{agent_scratchpad}")
])
# Create and run agent
agent = create_tool_calling_agent(llm, [search_tool], prompt)
executor = AgentExecutor(agent=agent, tools=[search_tool], verbose=True)
result = executor.invoke({"input": "What are the latest developments in AI agents?"})
LangChain’s strength is the uniformity of its abstractions. Whether you’re building a simple chain or a complex multi-agent system, you work with consistent interfaces.
LlamaIndex organizes around data concepts:
A typical LlamaIndex setup:
from llama_index.core import VectorStoreIndex, SimpleDirectoryReader
from llama_index.llms.openai import OpenAI
from llama_index.core.agent import ReActAgent
from llama_index.core.tools import QueryEngineTool
# Load and index documents
documents = SimpleDirectoryReader("./data").load_data()
index = VectorStoreIndex.from_documents(documents)
query_engine = index.as_query_engine()
# Create tool from query engine
query_tool = QueryEngineTool.from_defaults(
query_engine=query_engine,
name="documentation",
description="Search the product documentation for answers"
)
# Create agent
llm = OpenAI(model="gpt-4o")
agent = ReActAgent.from_tools([query_tool], llm=llm, verbose=True)
response = agent.chat("How do I configure authentication?")
LlamaIndex’s design shines when your primary challenge is making data accessible to an LLM.
| Feature | LangChain | LlamaIndex |
|---|---|---|
| Primary focus | General LLM orchestration | Data retrieval and indexing |
| Learning curve | Moderate to steep | Moderate |
| RAG capabilities | Good, via chains | Excellent, core strength |
| Agent frameworks | Multiple options (AgentExecutor, LangGraph) | ReAct, OpenAI agents |
| Data connectors | Many via community | Extensive, first-class support |
| Index types | Basic vector store support | Many specialized index types |
| Memory systems | Flexible, multiple options | Built into chat engines |
| Streaming | Full support | Full support |
| Evaluation tools | LangSmith integration | Built-in evaluation module |
| Async support | Comprehensive | Available |
LlamaIndex excels at data handling:
from llama_index.core import SimpleDirectoryReader
from llama_index.core.node_parser import SentenceSplitter
# Load from multiple sources
documents = SimpleDirectoryReader(
input_dir="./data",
recursive=True,
required_exts=[".pdf", ".docx", ".txt"]
).load_data()
# Sophisticated chunking
parser = SentenceSplitter(chunk_size=512, chunk_overlap=50)
nodes = parser.get_nodes_from_documents(documents)
LlamaIndex provides 100+ data loaders for everything from databases to Notion to Slack. Its node parsing preserves document structure and metadata intelligently.
LangChain handles data loading but with less sophistication:
from langchain_community.document_loaders import DirectoryLoader
from langchain.text_splitter import RecursiveCharacterTextSplitter
loader = DirectoryLoader("./data", glob="**/*.txt")
documents = loader.load()
splitter = RecursiveCharacterTextSplitter(chunk_size=500, chunk_overlap=50)
chunks = splitter.split_documents(documents)
LangChain’s loaders work well, but LlamaIndex’s data processing is more refined out of the box.
LangChain offers more agent architecture options:
LangGraph in particular enables sophisticated multi-agent systems:
from langgraph.graph import StateGraph
from langgraph.prebuilt import create_react_agent
# Define a stateful agent workflow with branching logic
# Supports cycles, conditional edges, and human-in-the-loop
LlamaIndex provides focused agent options:
LlamaIndex agents are typically simpler but integrate seamlessly with its query engines.
Both frameworks support custom tools, but their ecosystems differ:
LangChain has broader integration coverage for non-data tools:
LlamaIndex has deeper data integration:
LlamaIndex’s specialized focus on retrieval often translates to better out-of-the-box performance for RAG applications. Features like:
LangChain can achieve similar results but requires more manual configuration.
LlamaIndex’s response synthesizers are optimized for token efficiency:
# LlamaIndex offers different synthesis strategies
query_engine = index.as_query_engine(
response_mode="compact", # Minimize token usage
# Other options: "tree_summarize", "refine", "simple"
)
LangChain’s chains are flexible but may consume more tokens without careful prompt engineering.
LlamaIndex gets you to a working RAG prototype faster. LangChain takes longer initially but offers more customization for complex requirements.
LangChain is the better choice when:
Example use cases: Customer support agents with CRM integration, multi-agent research systems, automated workflow orchestration, chatbots with diverse tool access.
LlamaIndex is the better choice when:
Example use cases: Enterprise knowledge bases, document Q&A systems, research assistants, code documentation search, legal document analysis.
These frameworks aren’t mutually exclusive. A common pattern uses LlamaIndex for data handling within a LangChain orchestration:
from langchain.tools import Tool
from llama_index.core import VectorStoreIndex
# Create LlamaIndex query engine
index = VectorStoreIndex.from_documents(documents)
query_engine = index.as_query_engine()
# Wrap as LangChain tool
doc_tool = Tool(
name="documentation_search",
description="Search product documentation",
func=lambda q: str(query_engine.query(q))
)
# Use in LangChain agent with other tools
agent = create_tool_calling_agent(llm, [doc_tool, web_search, calculator], prompt)
This hybrid approach gives you LlamaIndex’s retrieval quality with LangChain’s orchestration flexibility.
Quick decision guide:
What’s your primary challenge?
How important is retrieval quality?
What’s your timeline?
How much customization do you need?
Both frameworks are mature, well-documented, and actively maintained. LlamaIndex recently raised significant funding and is expanding beyond pure retrieval. LangChain continues to evolve with LangGraph becoming increasingly powerful. Your choice should be guided by your specific requirements rather than general preference.
LangChain: Begin with the official tutorials and explore the LangGraph documentation for agent patterns.
LlamaIndex: Start with the starter tutorial and the RAG examples.
Both communities are active and helpful. Whichever you choose, you’re building on solid foundations for AI application development.
For a hands-on tutorial, check out our guide on building a RAG agent with LangChain. Coming tomorrow: a deep dive into agent memory systems.
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